📋Overview
Hereditary angioedema (HAE) is a rare genetic disorder characterized by recurrent episodes of severe swelling (angioedema) in various body parts including the skin, gastrointestinal tract, and airway. It is caused by a deficiency or dysfunction of the C1 esterase inhibitor protein, leading to excessive bradykinin production and increased vascular permeability. HAE is distinct from allergic angioedema and does not respond to typical allergy treatments.
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